Chronic ethanol treatment depletes glutathione regeneration capacity in hepatoma cell line HepG2
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منابع مشابه
Chronic ethanol treatment depletes glutathione regeneration capacity in hepatoma cell line HepG2
Chronic alcohol abuse is the leading cause of liver cirrhosis in western countries. Ethanol, even at lower concentrations, can cause pleiotropic effects at the cellular level such as the formation of reactive oxygen species (ROS) and DNA damage. Ethanol is oxidized to acetaldehyde by liver alcohol dehydrogenase and by a microsomal ethanol-oxidizing system which is dependent on CYP2E1. There are...
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ژورنال
عنوان ژورنال: Journal of Cellular Biotechnology
سال: 2016
ISSN: 2352-3689,2352-3697
DOI: 10.3233/jcb-15019